产品货号：
GS4466
中文名称：
重组小鼠IL-1α
英文名称：
Recombinant Murine Interleukin-1 Alpha
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 17.9kDa,a single non-glycosylated polypeptide chain containing 156 amino acids.
储存条件：冷冻（-20℃）
概述
Interleukin-1 alpha(IL-1α)is a non-secreted proinflammatory cytokine produced mainly by activated macrophages,as well as neutrophils,epithelial cells,and endothelial cells.It possesses metabolic,physiological,haematopoietic activities,and plays one of the central roles in the regulation of the immune responses.Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties.Among various species,the amino acid sequence of mature IL-1α s conserved 60%to 70%and human IL1 has been found to be biologically active on murine cell lines.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠IL-1α，IL-1α, Murine，Recombinant Murine Interleukin-1 Alpha
储存条件：冷冻（-20℃）
概述
Interleukin-1 alpha(IL-1α)is a non-secreted proinflammatory cytokine produced mainly by activated macrophages,as well as neutrophils,epithelial cells,and endothelial cells.It possesses metabolic,physiological,haematopoietic activities,and plays one of the central roles in the regulation of the immune responses.Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties.Among various species,the amino acid sequence of mature IL-1α s conserved 60%to 70%and human IL1 has been found to be biologically active on murine cell lines.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 2pg/ml,corresponding to a specific activity of>5.0×108 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rMuIL-1α as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS |
相关搜索：重组小鼠IL-1α，IL-1α, Murine，Recombinant Murine Interleukin-1 Alpha